About Prime-CKD

Chronic Kidney Disease (CKD) is one of the major causes of death in high income countries and its prevalence is growing rapidly. New therapies for the treatment of CKD have shown clear efficacy at a population level. Yet, individual patients respond differently with many patients showing suboptimal efficacy. This indicates that a ‘one size fits all’ approach is no longer sustainable. Currently there are no validated biomarkers (i.e. signal-substances that can be measured in blood or urine) in patients with CKD that aid in guiding optimal therapy for individual patients. Furthermore, there remains a large gap between biomarker research and actual implementation of biomarker based care in daily clinical practice.

“Individual and optimal treatment for every kidney patient; that is what we aim for.”

What is our objective?

The researchproject PRIME-CKD (Personalized drug Response: IMplementation and Evaluation in Chronic Kidney Desease) has a unique advantage to address the challenge we are facing as it builds on recent discoveries of new biomarkers to help guide optimal treatment to individual patients. The research must lead to new therapies for the treatment of CKD.

Objective of Prime CKD

Latest News

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One year of PRIME-CKD: where are we now?

In April and May the consortium has had two important meetings: the annual consortium meeting and the annual stakeholder meeting. On April 25 and 26 over 40 consortium members met in beautiful Valencia (Spain) to meet each other..
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CTIS application

In February, our Danish partners at the Steno Diabetes Center in Copenhagen completed the Clinical Trial Information System (CTIS) application at the European Medicine Agency in a joint effort with colleagues at the University Clinic Hamburg-Eppendorf...
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EMA Qualification

In 2023 PRIME-CKD project leader Hiddo Lambers Heerspink and Lesley Inker (Tufts Medical Center, Boston), co-authored an important paper in Nature Medicine on the use of GFR slope as a surrogate endpoint for kidney failure...

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